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Calprotectin Quantum Blue® Rapid Testing

A rapid quantitative Faecal Calprotectin testing platform for lower throughput requirements.

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Loading Quantum BlueThe Quantum Blue® rapid test combines the ease and speed of lateral flow technology (using a highly specific monoclonal antibody to calprotectin), with full quantitation by means of a small, dedicated telephone sized reading device.

The Quantum Blue® Calprotectin reader analyses the signal intensity from the test and control line to give a quantitative value and is standardised with the BÜHLMANN fCAL™ ELISA.

This diagnostic tool enables a rapid gatekeeper strategy based on calprotectin levels in patient stool samples to support the physician’s decision on whether to prepare patients for colonoscopy or to treat them for the symptoms associated with Irritable Bowel Syndrome (IBS).

This test is suitable when true quantitation is required but in a low sample throughput environment making it deal for Point of Care and clinic use.

Why Use Quantum Blue Calprotectin?

  • Provides a quantitative measurement of calprotectin in faecal samples
  • Simple and rapid extraction and test process
  • Results within 12 minutes
  • Supplied with a dedicated reader
  • Excellent correlation with the EK-CAL Calprotectin ELISA
  • Based on established lateral flow technology
  • Three kit formats available dependent on test range required:
    Quantum Blue® fCAL (LF-CAL25) – measurable range 30-300µg/g
    Quantum Blue® fCAL High Range (LF-CHR25) – measurable range 100-1800µg/g
    Quantum Blue® fCAL Extended Range (LF-CALE25) – measurable range 30-1000µg/g

  • Based on established lateral flow technology
  • Provides a quantitative measurement of Calprotectin in faecal samples but in a rapid test formatin (12 mins)
  • Results can be downloaded to the LIS
  • Simple and rapid extraction and test process
  • Compact benchtop reader
  • Excellent correlation with the market leading Bühlmann fCal® Calprotectin ELISA: uses a consistent cut off value (50µg/g)
  • Measurable range 30-300µg/g (LF-CAL25) or 100-1800µg/g (LF-CHR25) Calprotectin in stool samples
  • New Extended range kit (LF-CALE25) (30-1000µg/g) for use with Quantum Blue Two second generation instruments (Serial no. >1000)
    - Diagnosis and monitoring of therapy with a single test format
    - Simplify laboratory procedures with a single protocol across the concentration range
    - Improve stock management as one kit covers two requirements

The introduction of the Quantum Blue test into the Department has been very easy. Staff like using the system and the extraction step is made as easy and straightforward as possible with the Smart Prep stool extraction device.

Tracey Staughton, Clinical Scientist, Royal Berkshire Hospital

  • 2017 Quantum® Blue fCAL Brochure

    • PDF size: 9.32KB
    • Uploaded on: 27/01/2017

    Quantification of Faecal Calprotectin for Diagnosis and Monitoring of Inflammation in IBD

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  • A New Rapid Test For Fecal Calprotectin Predicts Mucosa Healing In Crohn’s Disease

    • PDF size: 11.19KB
    • Uploaded on: 19/01/2017

    Lobatón Ortega et al. Department of Gastroenterology. Bellvitge University Hospital. Barcelona. Spain, Poster ECCO

    Open File
  • A New Rapid Test For Fecal Calprotectin Predicts Mucosa Healing in Ulcerative Colitis

    • PDF size: 1.44MB
    • Uploaded on: 19/01/2017

    Lobatón Ortega et al. Department of Gastroenterology. Bellvitge University Hospital. Barcelona. Spain, Poster ECCO

    Open File
  • Calprotectin Revolution and Evolution

    • PDF size: 12.37KB
    • Uploaded on: 17/03/2017

    Open File
  • Converting from Quantum Blue to ELISA - Verification of Calprotectin ELISA Data

    • PDF size: 11.03KB
    • Uploaded on: 27/01/2017

    Open File

Usefulness of a rapid faecal calprotectin test to predict relapse in Crohn’s disease patients on maintenance treatment with adalimumab
Rocio Ferreiro-Iglesias, Manuel Barreiro-de Acosta, Aurelio Lorenzo-Gonzalez & Juan Enrique Dominguez-Muñoz
Scand J Gastroenterol. 2016;51(4):442-7

Faecal Calprotectin: comparative study of the Quantum Blue® rapid test and an established ELISA method
Liselotte Coorevits, Filip J. Baert and Hilde J.M. Vanpouke 
Clin. Chem. Lab. Med. 2012; 51:4

Validation of a point-of-care desk top device to quantitate fecal calprotectin and distinguish inflammatory bowel disease from irritable bowel syndrome. 
Michael J. Sydora, Beate C. Sydora, Richard N. Fedorak. 
Journal of Crohn's and Colitis (2012) 6, 207-214

A New Rapid Quantitative Test for Fecal Calprotectin Predicts Endoscopic Activity in Ulcerative Colitis.
Triana Lobatón Ortega, Francisco Rodríguez-Moranta, Jordi Guardiola Capón, Elena Sánchez Pastor, Lorena Rodríguez Alonso, Alexandra Ruiz Cerulla, Alicia López García. Department of Gastroenterology. Bellvitge University Hospital. Barcelona. Spain. 
DOI: 10.1097/MIB.0b013e3182802b6e

Evaluation of Prevent ID and Quantum Blue rapid tests for fecal calprotectin. 
Jan Hessels, Geke Douw, Duygu D. Yildirim, Gerrit Meerman, Margot A. van Herwaarden and Frank A.J.T.M. van den Bergh. 
Clin Chem Lab Med. 2012 Jan 13;50(6):1079-82. 

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