Nucleic Acids Research
Nucleic acids are one of the key building blocks of life. Nucleotides assembled into polymeric macromolecules like DNA and RNA serve to carry essential biological information for organism development and function. DNA encodes and stores the genetic master template from which RNA sequences are transcribed, and in the case of coding sequences these messenger RNAs (mRNAs) may be subsequently translated into proteins.
Studying the interactions of these nucleic acids has revealed complex, multi-faceted pathways of gene regulation and interaction. Changes in gene expression may be associated with various diseases and elucidating the mechanisms behind such dysregulation could help shape future therapies.
Wako offers a range of Ago antibody based products to study Ago protein expression and investigate the miRNA and mRNA that associate with Ago proteins in the RISC complex.
Reagents for the isolation of DNA and RNA. Nucleic acid extraction and isolation are crucial steps in genetic analysis, with results highly dependent on the quality of these steps.