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Recombinant Proteins

These recombinant proteins are well suited for use as standards in quantifying assays ELISA.

They include NGAL from Mouse, Rat, Dog, Pig, Monkey and Human.

NGAL is the first kidney injury or toxicity biomarker that can be measured in all the five standard animal models of basic research, medical research and drug development.

The unique range of BioPorto NGAL recombinant proteins and ELISAs available from Alpha Laboratories includes kits for Mouse, Rat, Dog, Pig, Monkey and Human NGAL.

Important applications of NGAL measurement for the pharmaceutical industry

The applications of BioPorto's animal NGAL products in drug development range from drug discovery to pre-clinical toxicity testing.
They can be used in pre-clinical studies to detect rises in NGAL concentrations in urine and blood and hence the extent of renal injury, including nephrotoxic injury.

  • Safety biomarker 
    NGAL levels rise from baseline if the kidney is injured
  • Efficacy biomarker
    NGAL levels fall if kidney damage is treated effectively

  • NGAL - Improve Kidney Research

    • PDF size: 10.43KB
    • Uploaded on: 18/09/2015

    Neutrophil gelatinase-associated lipocalin is a small, robust protein, which is released into and can be detected in both urine and blood upon kidney tubular damage.

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