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Allergens

The complete package for allergy diagnosis also includes a library of approximately 150 standardised allergens that are quality controlled, validated and standardized.

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Drugs

There have been multicentre studies on beta-Lactam antibiotics and NSAIDs performed and from these the European Network for Drug Allergy (ENDA) concluded that using the CAST® assays significantly reduces the need for potentially dangerous and costly drug provocation tests. It was also found that the CAST® assays are superior to sIgE determinations.

Bee/Wasp

The CAST® assays have 91% sensitivity and 95% specificity in Bee/Wasp testing. This means that it is possible to identify the actual culprit insect and support the clinical diagnosis in patients with ambiguous clinical history, skin tests or controversial sIgE. Recent studies show that the Flow CAST® is a very useful test for detecting double positivity due to CCD and is a promising tool to follow up specific immunotherapy (SIT).

Food

The CAST® assays are powerful tools for the discrimination and identification of cross reactivity between clinically relevant and irrelevant IgE. Recent studies confirm the BAT as a useful tool in the in vitro diagnosis of cow’s milk allergy due to its better sensitivity (91%) and specificity (90%) than sIgE (67% for both).

Food Additives

The diagnosis of food additive allergies is known to be very difficult as non immunological reactions are usually assumed to be the primary cause for the patients’ symptoms. The CAST® assays are the only assays available that can measure these allergies by the in vitro reaction.

  • Allergen Product List

    • PDF size: 1.56MB
    • Uploaded on: 10/07/2017

    Reference list of available BÜHLMANN Allergens

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  • Diagnosing Drug Allergy: A Rational Approach

    • PDF size: 10.26KB
    • Uploaded on: 17/03/2017

    Discussion by Dr Cathy van Rooyen, Allergy, Immunology & Virology Pathologist at AMPATH Pathology

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  • Drug Allergen Booklet

    • PDF size: 1.78MB
    • Uploaded on: 10/07/2017

    Details and References relating to the CAST Drug Allergens

    Open File
  • Inhalant, Venom, Food and Environmental Allergens Booklet

    • PDF size: 1.34MB
    • Uploaded on: 10/07/2017

    Details and References relating to the CAST Inhalant, Venom, Food and Environmental Allergens

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