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Calprotectin Turbidimetric High Throughput Testing

Speed, Quality and Flexibility in Calprotectin Quantification


BÜHLMANN fCAL® turbo is a flexible turbidimetric assay for faecal calprotectin applicable on many major clinical chemistry platforms.

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BÜHLMANN fCAL® turbo allows very rapid and flexible random access use, as well as being the ideal solution for high throughput applications in the routine laboratory.

The assay can be applied on many automated platforms in clinical chemistry and allows short turnaround time from stool sample to reportable result.

Assay protocols available:

  • Siemens:  Advia 1650, Advia 1800, Advia XPT, Dimension Vista500/1500*
  • Roche: Cobas 6000 (c501 & c502), Cobas 8000 (c701 & c702), Cobas c111
  • Abbott: Architect c series
  • Mindray: BS380, BS-200E, BS-400
  • Beckman: AU Series (AU400, AU480, AU640, AU680, AU2700, AU5400, AU5800) DxC600 and DxC800
  • ThermoFisher: Konelab30i, Indiko
  • Ortho: Vitros 5600
  • The Binding Site: Optilite
  • Horiba: ABX Pentra 400
  • IDS: iSYS

Other instrument protocols currently in validation, please enquire

Complete Automation

The combination of the test with the BÜHLMANN CALEX® Cap extraction device strongly simplifies the cumbersome procedure for stool pre-analytics and is adapted to the use on clinical chemistry analysers.

No additional pipetting and manual dilution steps are required anymore.

Recent modifications to the CALEX design enable it to be used on laboratory track systems to provide complete automation for faecal calprotectin testing with minimal hands on time.

Watch the CALEX Calprotectin Assay Automation Video

Contact us for the application notes that your track engineer will require.

Method                                 

Sample Type                         

Kit Format

                                               

 

Sample Preparation           

Reagent on Board             

Calibration                            

Calibration Range             

Measuring Range              

Sample Volume                 

Time to Result

Applicable                           

Particle-enhanced turbidimetric immunoassay (PETIA)

Faecal extracts

2 reagents; wedge bottles for direct loading on many platforms

Reagents last for ~200 tests; platform dependent

All assay components are also available individually

CALEX® Cap extracts can be used directly without additional dilution

Stable for at least 60 days

Stable for up to 60 days

0-2000 μg/g

20-8000 μg/g

~10 µl Extract (1:500)

~10 minutes

On many major platforms

 

  • Analytical and diagnostic performance of two automated fecal calprotectin immunoassays for detection of inflammatory bowel disease

    • PDF size: 9.45KB
    • Updated on: 04/07/2018

    De Sloovere et al 2016

    Open File
  • Analytical Performance of a Fecal CALPROTECIN (fCAL) PETIA Test

    • PDF size: 334.13KB
    • Updated on: 04/07/2018

    Open File
  • BÜHLMANN fCAL® turbo Correlation

    • PDF size: 11.84KB
    • Updated on: 04/07/2018

    Faecal Calprotectin Assay Proves Consistent between Multiple Analysers

    Open File
  • Calprotectin Revolution and Evolution

    • PDF size: 12.37KB
    • Updated on: 04/07/2018

    Open File
  • Diagnostics for Digestive Health Management

    • PDF size: 10.12MB
    • Updated on: 10/07/2018

    Open File
  • fCAL turbo datasheet

    • PDF size: 9.48KB
    • Updated on: 04/07/2018

    Open File
  • fCAL turbo® flyer

    • PDF size: 10.71KB
    • Updated on: 04/07/2018

    Immunoturbidimetric Faecal Calprotectin Assay

    Open File
  • The Way to Total Automation of Calprotectin Measurement In Faeces with BÜHLMANN fCAL®turbo

    • PDF size: 10.12KB
    • Updated on: 04/07/2018

    Schallberger et al. Poster - Abstracts Swiss MedLab 2016

    Open File
  • BÜHLMANN fCAL® turbo Faecal Calprotectin Assay on Abbott Architect C8000

    • PDF size: 9.10KB
    • Updated on: 04/07/2018

    Mary O’Connell B.Sc., M.Sc., Biochemistry Laboratory, Mercy University Hospital, Cork, Ireland

    Open File
  • The Evolution of Calprotectin Testing at James Cook University Hospital: fCAL turbo on the Siemens Advia 2400 XPT.

    • PDF size: 10.37KB
    • Updated on: 04/07/2018

    Mr Andrew Teggert, Clinical Scientist, James Cook University Hospital, Middlesbrough

    Open File
  • Calprotectin Home vs. Laboratory Test

    • PDF size: 6.92KB
    • Updated on: 04/07/2018

    Biochemistry Department, Mercy University Hospital - Case Study from Leading Edge 2018 Issue 1

    Open File
  • Calprotectin and Clinical Correlation

    • PDF size: 11.94KB
    • Updated on: 05/07/2018

    Biochemistry Department, Mercy University Hospital - Case Study from Leading Edge 2018 Issue 1

    Open File
  • Evaluation of the BÜHLMANN fCAL Turbo Faecal Calprotectin Assay on the Abbott Architect C8000. Comparison to the Phadia EliA and the IBDoc® home test kit.

    • PDF size: 1.43MB
    • Updated on: 04/07/2018

    MSc Research Project Scientific Paper, Mary O’ Connell, Eithne Barden, Biochemistry Laboratory, Mercy University Hospital, Cork, Republic of Ireland.

    Open File
  • Bringing Calprotectin Testing In-house on the Abbott Architect C8000

    • PDF size: 8.56KB
    • Updated on: 04/07/2018

    Mary O’Connell née Deasy, Biochemistry Department Mercy University Hospital Cork, Ireland

    Open File
  • Laborgemeinschaft 1 brings Calprotectin Testing In-house with BUHLMANN fCAL® turbo

    • PDF size: 10.55KB
    • Updated on: 04/07/2018

    Interview with Carmela Gugliotta (BMA), Laborgemeinschaft 1, Rautistrasse 11, 8047 Zurich, Switzerland

    Open File
  • Introducing in-house Calprotectin Testing Directly on the Roche cobas® c702

    • PDF size: 10.49KB
    • Updated on: 04/07/2018

    Rosie Forster and Karen Smith, Clinical Biochemistry, Queen Elizabeth Hospital Birmingham

    Open File
  • Verification and implementation of faecal calprotectin using the BÜHLMANN fCAL® turbo assay

    • PDF size: 12.29KB
    • Updated on: 04/07/2018

    Evans et al., Heart Of England NHS Foundation Trust. Use on the Abbott ARCHITECT platform.

    Open File
  • City Hospital Triemli Optimizes Laboratory Workflow For Calprotectin Testing

    • PDF size: 10.40KB
    • Updated on: 04/07/2018

    Interview with Anita Grünauer (BMA) et al., Institute for Laboratory Medicine, City Hospital Triemli, Zurich

    Open File
  • Evaluation of the BÜHLMANN fCAL™ turbo Calprotectin Method on the Roche Cobas 6000 (c501)

    • PDF size: 10.12KB
    • Updated on: 04/07/2018

    Poster ACB Focus 2017: P Bowe, F Leslie, S Slack, Cumberland Infirmary, Carlisle

    Open File
  • Children’s Hospital of Zurich introduces fCAL turbo on the Beckman UniCel DxC 600

    • PDF size: 10.62KB
    • Updated on: 04/07/2018

    Interview with Maria Barbieru Deputy Senior Biomedical Analyst, Department of Clinical Chemistry and Biochemistry, Children’s Hospital of Zurich

    Open File
  • Evaluation of the BÜHLMANN fCAL® turbo test on the Roche Cobas® c501

    • PDF size: 11.47KB
    • Updated on: 04/07/2018

    Interview with Yvonne Schallberger, Bioanalytica Lucerne 2

    Open File
  • On Board with fCAL® turbo at Cumberland Infirmary

    • PDF size: 12.02KB
    • Updated on: 04/07/2018

    Pamela Bowe describes the evolution of calprotectin testing in the Department of Biochemistry

    Open File

The Way to Total Automation of Calprotectin Measurement in Faeces with BÜHLMANN fCALl® turbo and CALEX® Cap on the Roche Cobas C501.
Yvonne Schallberger, Yvonne Staiger, Marius Ruessi, Lukas Bestmann
Bioanalytica, St.Anna-Strasse36, CH-6006 Lucerne, Switzerland
Swiss Union of Laboratory Medicine
Abstracts Swiss MedLab 2016

 

A Novel Turbidimetric Immunoassay for Fecal Calprotectin Optimized for Routine Chemistry Analyzers
T Nilsen et al. J Clin Lab Anal. 
University of Uppsala and the Karolinska Institute Stockholm

 

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