Supporting New Standards of Care for IBD with the first CE marked Calprotectin Patient Self-Test
Managing chronic conditions such as diabetes and hypertension through patient self-testing has become common place.
It is now also possible for sufferers of inflammatory bowel disease (IBD) to manage their condition from home.
New sophisticated technology enables patients to perform quantitative calprotectin tests themselves and then use their smartphones to read the results.
Alpha Laboratories has expanded its offering of BÜHLMANN Calprotectin tests with the launch of IBDoc®, the first CE marked Calprotectin home test.
Under the guidance of clinicians, regular monitoring is now possible for IBD patients in the comfort of their own home. This allows for a customised, patient centric approach for therapy and disease management helping to predict possible relapse and assisting with therapy optimisation.
85% of respondents prefer the IBDoc™ test over other methods.
Calprotectin home testing ..was very well received among the tested users (100% satisfaction)
IBDoc provides a customised, patient centric approach for
management of disease and therapy.
Easy as 1-2-3
The new BÜHLMANN IBDoc® system, now available from Alpha Laboratories, provides sophisticated technology that enables your IBD patients to perform quantitative calprotectin testing themselves, in just three easy steps, reading the results using their smartphones.
- Process the sample with the CALEX® Valve extraction device.
- Apply the extracted sample to the calprotectin cassette
- Use the smartphone CalApp® to read and calculate the result and send it to the gastroenterologist via the secure IBDoc® Portal.
More Regular Patient Monitoring
IBDoc provides a practical way for more frequent monitoring of patients in the privacy of their own home.
Under the guidance of clinicians, more regular patient monitoring can help predict potential relapse and assist in therapy optimisation. This approach allows for a customised, patient centric approach for management of disease and therapy.
1. Prepare the Test
To start the test procedure the patient logs into the downloaded CalApp® on their smartphone with their IBDoc® account username and password. They then collect a stool sample with the easy to use faecal collection paper sheet included in the IBDoc® Test Kit.
2. Extract the Sample
The sampling pin of the CALEX® Valve extraction device is dipped into the stool sample a few times with a twisting motion. This collects a defined amount of stool in the grooves of the CALEX® Valve pin. The pin is placed back into the tube through the upper funnel.
3. Load the Test Cassette
The CALEX® Valve tube is applied onto the test cassette and a precise amount of extract is released by turning the lever. After a few seconds, when the membrane strip of the cassette gets visibly soaked, the lever is closed.
4 Read the Test Cassette
Results are read using the smartphone camera. Placing the camera above the cassette focuses and automatically takes a picture. The image is analysed through a sophisticated image processor and a quantitative result is calculated by the CalApp®.
5 Save the Test Result
Using a traffic light code system the result is classified as NORMAL, MODERATE, or HIGH. All the results performed on one smartphone are saved locally and can be accessed at any future time.
6 Doctor Is Notified
The result taken with the CalApp® is automatically transferred to the IBDoc® Portal and the patient’s doctor is immediately notified. Depending on the test result the doctor can communicate with the patient to advise on further therapeutic steps to be taken.
- First CE marked Calprotectin Home Test
- Excellent correlation with laboratory based tests
- Quantitative rapid test with measurement of calprotectin in the range 30 – 1000µg/g
- Simple sample preparation devices minimises pre-analytical errors
- All components contained within the kit to perform a test with simple instructions
Pictorial IFU guide
Two stool collection papers
Camera calibration card/ reading template
CALEX value extraction device
Individually sealed test cassette
- User friendly App with Phone calibration
Easy Sample Extraction and Dispensing
The CALEX® Valve allows patients to process their own samples without the need for vortex mixing, centrifuging or pipetting. The valve at the base of the device dispenses a precise amount of liquid onto the lateral flow test device. After 12 minutes the calprotectin assay result is read using the smartphone and the data is transmitted to the clinician via a secure web portal.
Personal Portal for Direct Management by the Clinican
The IBDoc Portal is a secure, encrypted, user friendly application for clinical professionals to manage their IBD patients.
Each patient test profile can be tailored by the clinician:
- Threshold values for the traffic light system
- Choose for the patient to see the traffic light interpretation, the actual calprotectin value or hide the results completely
- Set the frequency of the tests for the patient.
Excellent Correlation of Results
IBDoc provides consistent results that correlate with other BÜHLMANN Calprotectin assays:
- BÜHLMANN Quantum Blue® fCAL
- BÜHLMANN fCAL® ELISA
- BÜHLMANN fCAL® turbo
Colitis Monitoring Could Soon Start at Home
Gastroenterology and Endoscopy News: AUGUST 2015 | VOLUME: 66:8
Home-testing of faecal calprotectin using the IBDoc™ system: a comparative pilot study
Parr, H et al. King's College Hospital NHS Foundation Trust, Poster: BSG 2016,
An evaluation of patient satisfaction with IBDoc calprotectin home test system
Fitzgerald et al. Mercy University Hospital, Cork, Ireland: ECCO 2-17 Abstract N804
Usability of a home-based test for the measurement of fecal calprotectin in asymptomatic IBD patients
Bello et al. Dig Liver Dis. 2017 May 19. pii: S1590-8658(17)30886-1
CalApp® is the smartphone app used with the IBDoc® Calprotectin Home Test. It is available for Android and iOS devices*.
As part of the IBDoc® System, CalApp® has been validated for the smartphones listed here.
*CalApp® is not available for download on non-validated phones and technical specifications or model nomenclature might differ in different countries.
Supported Apple Devices
|| Model Number
|iPhone 6 plus
|iPod Touch 5th Generation
Download the App
Supported Samsung Devices
|| Model Number
|Galaxy A3 (2014)
|Galaxy A3 (2016)
|Galaxy Core Prime LTE
Download the App
Other Supported Devices
HTC One (M7)
Huawei P8 Lite Model ALE-L21
LGE G3 Model LG-D855
LGE G4 Model LG-H815
Sony Xperia Z3compact Model E5823
Sony Xperia Z4compact Model D5803
The IBDoc® Portal is the web portal used by clinicians to help manage their IBDoc® patients and can be accessed via any standard web browser under www.ibdoc-portal.net.
IBDoc Portal Minimal System Requirements
||5 or higher
||4 or higher
||20 or higher
||16 or higher
||8 or higher
||5 or higher
||1 or higher
||20 or higher
IBDoc Frequently Asked Questions
- Is the IBDoc available over the counter?
No, it is only available through clinicians
- What if I upgrade my phone?
If the phone is changed to another approved phone from the list then the same user ID and password will apply.
The local results history will be lost as this is stored on the phone, however it is still visible in the portal
- What happens if I don’t have a WiFi connection?
The result is stored until WiFi is re-established and then the result is sent to the portal
- How secure is the data?
There is a two way encrypted communication between the App and the portal with test results backed daily.
No patient information is visible to anyone other than the clinic
- What level are the traffic light thresholds set at?
The categories are defaulted to:
The levels are customisable by the clinician for each individual patient
- What happens if I get a red result?
Contact the clinic using the information provided under the help/ contact information section for advice.