This product is for Professional Use only and not for sale to the general public for home use.
Please log in with a business account to purchase.
(R,R)-3,4,5-Trifluorophenyl-NAS Bromide Maruoka chiral phase-transfer catalyst optically active spiro ammonium salt 500mg Wako
Product code: 207-15923
Pack Size: 500mg
CE Verified: Research Use Only
Contact us
This is not a regular stock item and therefore not subject to our standard delivery schedule. Please contact us on +44 (0) 2380 483000 for advice on expected delivery date.
Product Information
(R,R)-3,4,5-Trifluorophenyl-NAS Bromide Maruoka chiral phase-transfer catalyst 500mg produced by Wako Pure Chemicals
Chiral phase-transfer catalysts, which are optically active spiro ammonium salts with 2 binaphthyl rings that allow for easy molecule designing, were invented by Professor Maruoka of the Kyoto University. (R,R)-3,4,5-Trifluorophenyl-NAS Bromide shows high catalytic activity and high enantioselectivity in asymmetric alkylation of alpha-amino acid derivatives 1. By using (R,R)-3,5-Bistrifluoromethylphenyl-NAS Bromide, beta-hydroxy alpha-amino acid derivatives which are important chiral units of biologically active peptides are obtained in good yield by the aldol reaction of glycine derivatives with aldehydes. It was found that erythro isomers, which are major products, were obtained with high enantioselectivity 2.
Features:
1. The rational molecular design of C2-symmetric chiral quaternary ammonium salt
2. Reaction under mild organic / aqueous biphase conditions
3. Catalysing the asymmetric alkylations of alpha-amino acid derivatives and the direct asymmetric aldol reactions of glycine schiff base with aldehydes to the corresponding beta-hydroxy-alpha-amino acid derivatives
References:
1. Ooi T., Takeuchi M., Kameda M. and Maruoka K. : J. Am. Chem. Soc., 122 (21), 5228-5229 (2000).
2. Ooi T., Taniguchi M., Kameda M., Maruoka K. : Angew. Chem. Int.
Molecular Formula=C56H34BrF6N
Molecular Weight=914.77
CAS No=534570-50-8
Store at room temperature
For organic synthesis
Chiral phase-transfer catalysts, which are optically active spiro ammonium salts with 2 binaphthyl rings that allow for easy molecule designing, were invented by Professor Maruoka of the Kyoto University. (R,R)-3,4,5-Trifluorophenyl-NAS Bromide shows high catalytic activity and high enantioselectivity in asymmetric alkylation of alpha-amino acid derivatives 1. By using (R,R)-3,5-Bistrifluoromethylphenyl-NAS Bromide, beta-hydroxy alpha-amino acid derivatives which are important chiral units of biologically active peptides are obtained in good yield by the aldol reaction of glycine derivatives with aldehydes. It was found that erythro isomers, which are major products, were obtained with high enantioselectivity 2.
Features:
1. The rational molecular design of C2-symmetric chiral quaternary ammonium salt
2. Reaction under mild organic / aqueous biphase conditions
3. Catalysing the asymmetric alkylations of alpha-amino acid derivatives and the direct asymmetric aldol reactions of glycine schiff base with aldehydes to the corresponding beta-hydroxy-alpha-amino acid derivatives
References:
1. Ooi T., Takeuchi M., Kameda M. and Maruoka K. : J. Am. Chem. Soc., 122 (21), 5228-5229 (2000).
2. Ooi T., Taniguchi M., Kameda M., Maruoka K. : Angew. Chem. Int.
Molecular Formula=C56H34BrF6N
Molecular Weight=914.77
CAS No=534570-50-8
Store at room temperature
For organic synthesis
Specification
- Brand FUJIFILM Wako Chemicals Europe GmbH – Lab Chem
- Sterile N
- CE Certified Research Use Only
- Warranty Period Standard Terms Apply
- Is product classified as dangerous goods? No
- Does the product contain latex? Unspecified
- Source Species NULL
- CAS Number 534570-50-8
- Application Organic Synthesis
- Molecular Formula C56H34BrF6N
- Form 500mg
- Concentration NULL
- Purity NULL
- Marketed Grade NULL
- Molecular Weight 914.77
- Shelf Life NULL
- Species Reactivity NULL
- Preparation Form White-brown crystalline powder
Storage Details
- Pack Description 500mg
- Shipping Condition Direct
- Storage Condition Special
- Pack Length (m) 0.06
- Pack Width (m) 0.06
- Pack Height (m) 0.06
- Pack Weight (kg) 0.00
You may also be interested in
1 ? activePage - 1 : activePage" >Prev
Next