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Anti-4R-Tau 4-Repeat Tau isoform Mouse monoclonal antibody clone 3E8-1A6 for Human Tau WB IP Wako
Product code: 013-26591
Pack Size: 50µl
CE Verified: Research Use Only
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Product Information
Anti-4R-Tau mouse monoclonal antibody clone 3E8-1A6 produced by Wako Pure Chemicals
Tau is a microtubule-associated protein, mainly expressed in neurons in the central nervous system, and regulates stabilisation of microtubules. In the brains of Alzheimer’s disease patients, neurofibrillary tangles are formed with are composed of accumulated phosphorylated forms of Tau. The degree of these tangles correlates to the severity of dementia. Based on this finding, Tau has been investigated to find out the aetiology and discover drugs for Alzheimer’s disease. Tau is classified into 3R-Tau and 4R-Tau which have 3 and 4 microtubule associated domains respectively. This antibody specifically recognises 4 Repeat Tau.
Wako’s Anti-4R-Tau monoclonal primary antibody was raised in mouse using GKVQIINKKLDLSNVQSKC representing 273-291 aa of Human Tau as antigen
Reacts with Human 4R-Tau protein
Clone 3E8-1A6
Isotype IgG1
Protein A-affinity purified
Concentration 1.0 mg/ml
Formulation: PBS with 50% glycerol containing 0.05% ProClin 300.
Suggested working concentrations:
Western Blot 1:1000-2000
Immunoprecipitation 1:100
Pack size – 50µl.
Store at -20°C.
For Research Use Only.
Tau is a microtubule-associated protein, mainly expressed in neurons in the central nervous system, and regulates stabilisation of microtubules. In the brains of Alzheimer’s disease patients, neurofibrillary tangles are formed with are composed of accumulated phosphorylated forms of Tau. The degree of these tangles correlates to the severity of dementia. Based on this finding, Tau has been investigated to find out the aetiology and discover drugs for Alzheimer’s disease. Tau is classified into 3R-Tau and 4R-Tau which have 3 and 4 microtubule associated domains respectively. This antibody specifically recognises 4 Repeat Tau.
Wako’s Anti-4R-Tau monoclonal primary antibody was raised in mouse using GKVQIINKKLDLSNVQSKC representing 273-291 aa of Human Tau as antigen
Reacts with Human 4R-Tau protein
Clone 3E8-1A6
Isotype IgG1
Protein A-affinity purified
Concentration 1.0 mg/ml
Formulation: PBS with 50% glycerol containing 0.05% ProClin 300.
Suggested working concentrations:
Western Blot 1:1000-2000
Immunoprecipitation 1:100
Pack size – 50µl.
Store at -20°C.
For Research Use Only.
Specification
- Brand FUJIFILM Wako Chemicals Europe GmbH – Lab Chem
- Sterile N
- CE Certified Research Use Only
- Warranty Period Standard Terms Apply
- Is product classified as dangerous goods? No
- Does the product contain latex? Unspecified
- Host Mouse
- Clonality Monoclonal
- Application Western Blot, Immunoprecipitation
- Form 50µl
- Specificity 4R Tau
- Species Reactivity Human
- Preparation Form PBS with 50% glycerol containing 0.05% ProClin 300.
- Concentration 1mg/ml
- Clone Number 3E8-1A6
- Isotype IgG1
- Source Species Human
- Shelf Life NULL
- Cross Reactivity Human
- Immunogen GKVQIINKKLDLSNVQSKC representing 273-291 aa of Human Tau
Storage Details
- Pack Description 50µl
- Shipping Condition Dry Ice
- Storage Condition -20
- Pack Length (m) 0.015
- Pack Width (m) 0.015
- Pack Height (m) 0.022
- Pack Weight (kg) 0.00