Vitamin B6 quantitative assay for plasma BÜHLMANN 100 tests for deficiency or overdose assessment

Vitamin B6 (Pyridoxal 5’ phosphate (PLP) is a water soluble compound found in many different foods, the biologically active form and is essential for the function of more than 100 enzymes as a co-enzyme. Therefore signs of deficiency are manifold and severe states of deficiencies are rare and mostly associated with deficiency of vitamin B12 and folate. Low vitamin B6 status is associated with a large number of diverse diseases including cardiovascular disease, cancer, cognitive function and premenstrual syndrome.
People at risk of Vitamin B6 deficiency include those with impaired renal function, autoimmune disorders including rheumatoid arthritis, malabsorbtive diseases like celiac disease, crohn’s disease and ulcerative colitis and alcohol dependence. Furthermore, severe interactions with medications are known for people using Cycloserine (tuberculosis antibiotic), antiepileptic medications like Valproic Acid and Carbamacepin, and Theophylline used for treatment of asthmatic diseases.
The BÜHLMANN Vitamin B6 enzymatic assay (KK-VB6) is intended for the quantitative determination of Pyridoxal 5’-Phosphate (PLP, vitamin B6) in EDTA plasma and allows for detection of potential vitamin B6 deficiency or overdose.
Product Details:
Product Code: KK-VB6
Sample Type: EDTA plasma. Draw blood into an EDTA venipuncture tube. Centrifuge for 15 minutes at 1000 x g at 2-8 °C immediately after collection or after storage at 2-8 °C for up to 12 hours protected from light. Avoid long exposure to light. After centrifugation, collect the plasma in polypropylene tubes and store at ≤-20 °C if not assayed immediately. PLP in plasma will remain stable for at least 3 months if stored at ≤-20°C. Avoid repeated freeze-thaw cycles.
Test Range: 9 - 250nmol/l
Sensitivity: 9nmol/l
Test Time: 45 minutes
Number of tests: 100 tests
Ce marked: Yes
Storage: 2-8C
Note: A yellow coloration of the reconstituted Substrate reagent will not influence performance. Visible signs of microbial growth and gross turbidity in the reagents may indicate degradation and warrant discontinuation of use.