This product is for Professional Use only and not for sale to the general public for home use.
Please log in with a business account to purchase.

Sign In

Serum Adalimumab Quantitative lateral-flow test for BÜHLMANN Quantum Blue reader for measuring trough Adalimumab levels. Range 1.3.35µg/ml

Product code: LF-TLAD25

Pack Size: 25 tests
CE Verified: CE IVD
Contact us

This is not a regular stock item and therefore not subject to our standard delivery schedule. Please contact us on +44 (0) 2380 483000 for advice on expected delivery date.

Product Information

BÜHLMANN Quantum Blue® Adalimumab is an in vitro diagnostic lateral flow immunoassay for the quantitative determination of trough levels of adalimumab in serum samples.

The assay serves as an aid to therapeutic drug monitoring in patients with inflammatory bowel disease (IBD) under adalimumab therapy, in conjunction with other clinical and laboratory findings.
Quantum Blue Adalimumab is combined with the Quantum Blue Reader.
The test is designed for the selective measurement of adalimumab by a sandwich immunoassay.

Recombinant tumor necrosis factor alpha (TNFα) is conjugated to gold colloids. On the test cassette the gold conjugate is released from a pad into the reaction system as the sample is applied. Adalimumab present in the sample will bind to the gold conjugate. A monoclonal antibody, highly specific for adalimumab, is immobilised on the analytical membrane and will capture the complex of gold conjugate and the adalimumab analyte, resulting in a colouring of the Test Line (T). The remaining free TNFα-gold conjugate will bind to the Control Line (C). The signal intensities of the Test Line (T) and the Control Line (C) are measured quantitatively by the Quantum Blue Reader.

Specimen collection and storage: Collect blood into plain venipuncture tubes without any additives avoiding haemolysis and let the serum clot at room temperature for at least 20 and for up to 60 minutes. Centrifuge at room temperature at ~2000 x g for 15 minutes. Decant the serum. Serum samples can be stored refrigerated at 2-8 C for up to 14 days. For longer storage, keep serum samples at ≤-20 C. These samples are stable for at least 3 months at ≤-20 C.

Interpretation of Results: The determination of adalimumab trough levels in patient serum samples can support therapy monitoring of IBD patients. Generally, trough levels in serum that reach a value of 5 µg/mL and above, during therapy maintenance, correlate well with clinical remission, low CRP values, as well as endoscopic healing of the gut mucosa. A plateau for endoscopic remission was demonstrated for adalimumab trough levels above 12 µg/mL. Values below 5 μg/mL Sub-therapeutic adalimumab levels in serum suggest pharmacokinetic failure. Therapy adjustment, taking into account available clinical and laboratory findings, should be considered. Values between 5-12 µg/mL Therapeutic adalimumab trough levels may serve as an indication for continuing therapy with the current dosage, in patients in IBD disease remission. Values above 12 µg/mL Supra-therapeutic adalimumab trough levels may serve as an indication for dose reduction in conjunction with the clinical picture, in patients in IBD disease remission.

The reagents supplied with this kit are optimised tomeasure trough levels of adalimumab in diluted serum samples.
Samples from patients switching from certolizumab (Cimzia®) therapy should not be tested directly with Quantum Blue Adalimumab, as cross-reactivity may occur. Allow certolizumab (Cimzia®) trough levels to fall at least below 2.9 μg/mL.


  • Brand BÜHLMANN
  • Sterile N
  • CE Certified CE IVD
  • Warranty Period Standard Terms Apply
  • Is product classified as dangerous goods? No
  • Does the product contain latex? Unspecified
  • Measuring Range 1.3 - 35µg/ml
  • Sensitivity 0.8µg/ml
  • Contents 25 individually sealed test cassettes, 1x10ml chase buffer, 2 x 0.5ml vials of high and low control, 2 RFID cards (one green and one white)
  • Detected Chemical serum adalimumab

Storage Details

  • Pack Description 25 tests
  • Shipping Condition Ambient
  • Storage Condition Fridge
  • Pack Length (m) 0.22
  • Pack Width (m) 0.15
  • Pack Height (m) 0.12
  • Pack Weight (kg) 1.00

Require further information for this product? Get in touch below

How can we contact you? Please confirm accepted methods:

* Required Fields

Your request will be forwarded to the relevant department to assist with your enquiry. By clicking 'Send Enquiry' you are authorising Alpha Laboratories to process your information and use it to contact you so that we may respond to your request, as well as to communicate with you regarding our products and services.

Submitting your details indicates that you agree to our Privacy Policy.