QuickGene-Mini8L DNA RNA Extractor Instrument Semi-Automated Large Sample Size for DNA and RNA Extraction

The QuickGene series of instruments and kits provides a novel, innovative method for DNA and RNA extraction from a vast number of sample types, all without the need for strong centrifugation steps, or centrifugation at all.

QuickGene operates in a similar manner to centrifugation methods, isolating DNA from samples by forcing said samples through a membrane. This membrane has a hydrophilic surface and therefore retains other hydrophilic molecules, such as DNA or RNA depending on the target, but does not retain hydrophobic molecules such as proteins. The result is that unwanted molecules are washed through the membrane, whereas DNA or RNA are retained in the membrane and eluted into collection tubes.

However, the major difference comes from the QuickGene porous membrane itself, which is 10 times thinner than conventional, usually glass fibre based, membranes. Traditional glass fibre membranes are roughly 1000µm in thickness and require large forces, created by centrifugation, to force samples through this thick membrane. QuickGene on the other hand, uses porous membranes only 100µm thick, requiring much weaker force to push samples through the membrane. This force is generated by compressed air, supplied by the QuickGene nucleic acid instruments, such as the QuickGene Mini8L. The use of compressed air eliminates the need for centrifugation and allows weaker forces to be applied to the sample allowing for improved preservations, and therefore increased length, of nucleic acid chains, whilst the innovative membrane retains high nucleic acid purity and yield.

The QuickGene Mini8L nucleic acid extraction device is designed for the semi-automated extraction of nucleic acids from larger samples of up to 2mL. The Mini8L can process up to 8 samples at a time, with operation as simple as turning the knob to turn the system on and off. Once processed, the isolated and purified DNA is suitable for use in many downstream analyses including, among others: sequencing, PCR, blotting, DNA micro arrays and digestion.

Through the use of the following corresponding QuickGene DNA extraction kits a wide variety of sample types can be processed, including:

•633-23539 DB-L DNA Whole Blood Kit L:

•Human Blood Samples
•Animal Blood Samples

•632-29589 DT-L DNA Tissue Kit S:

•Saliva
•Liver
•Lung
•Kidney
•Hard Tissues (Teeth and Bone)
•Hair
•Nails
•Plant Tissues

The QuickGene Mini8L can also be adapted for use with small samples and kits through the use of an adaptor (part number 40321301409), further expanding its capabilities.

Specifications

•Sample Throughput: 1-8 Samples per cycle
•Maximum Sample Volume: 2mL
•Width: 280mm
•Length: 260mm
•Height: 300mm
•Weight: 3.3kg
•Voltage: 100-240V
•Operating Temperature: 15-30C