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Neutrophil Gelatinase-Associated Lipocalin (NGAL)

Neutrophil gelatinase-associated Lipocalin is released from activated neutrophils in inflammation or infection, certain epithelial cancers and dramatically from renal tubular cells in response to ischaemic or nephrotoxic injury.

In humans and other mammals renal expression of Neutrophil Gelatinase-associated Lipocalin or Lipocalin-2 (NGAL) is dramatically increased after acute kidney injury (AKI) and NGAL monomer is then released into both urine and plasma.

Evidence is rapidly accumulating to show that the rise in NGAL monomer levels can detect acute kidney injury (AKI) within 2 hours of onset.

For more information about the significance of NGAL in human health and disease please visit our dedicated NGAL web site.

Visit www.ngaltest.co.uk

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