UK Freephone Orders
0800 387732
9am to 5pm Mon-Fri
International Orders
+44 2380 487209
Select Your Country

Glucagon-like peptide-1 (GLP-1)

Those peptides involved in the regulation of appetite and satiety have become a focus for potential therapies in the fight against obesity and associated diseases.

GLP-1 is released by the intestine in response to food and stimulates secretion of insulin from the pancreas which enables the body to store and use the glucose produced by digestion. GLP-1 also acts via the vagal pathway to inhibit gastric acid secretion and gastric emptying which serve to increase satiety. Receptors for GLP-1 are also found in the brain, predominantly expressed in the Nucleus of the solitary tract and arcuate nucleus – regions associated with appetite and feeding behaviour. Analogues of GLP-1 such as Exendin-4, a peptide present in the venom of the Gila monster, have been keenly studied and are associated with weight loss.

  • GLP-1 And EXENDIN-4 in Focus

    • PDF size: 8.01KB
    • Uploaded on: 21/09/2015

    Open File
Set Descending Direction

Items 1 to 12 of 28 total

Grid List
Set Descending Direction

Items 1 to 12 of 28 total

Grid List