PCR kits to detect the most prevalent β-Lactamase genes, when used along with standard culture.
Antibiotic resistance is an increasing threat to global public health. With the support of genetic identification of resistance mechanisms, infection control and active surveillance play a critical role in preventing the spread of resistance through the population and lowering mortality rates.
Gram-negative organisms resistant to β-lactams often produce multiple β-lactamases, making phenotypic detection of medically important β-lactamases difficult. Identification of these resistance mechanisms is key in controlling the spread of infection and can help determine the best therapeutic options for patients. With antibiotic resistant bacteria, knowing what NOT to prescribe can be a critical piece of information that leads to more precision in the treatment of infections.
β-lactamase ID enables rapid detection of 9 different β-lactamase genes: CMY, DHA, CTX-M-14, VIM, NDM, IMP, KPC, CTX-M-15 and OXA-48. This kit will help to provide up-to date information for hospital surveillance programs by identifying which Gram-negative resistant bacterial strains are present.
Proper identification is essential for infection control programs and in the selection of optimal β-lactam therapy.
ampC ID provides a rapid and accurate method to detect 6 of the most prevalent plasmid-mediated ampC genes: MOX, DHA, ACC, EBC, FOX and CMY.
The kit will provide results in one hour after extraction from a cultured sample.