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Anti Human Iba1 Mouse IgG2b Monoclonal Antibody (NCNP27) 50µ for Immunochemistry Wako
Product code: 013-27593
Pack Size: 50µL
CE Verified: Research Use Only
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Product Information
Anti-Iba1 (NCNP27) mouse monoclonal antibody, manufactured by FUJIFILM Wako Pure Chemical Corporation.
Ionized calcium binding adaptor molecule 1 or Iba1 is specifically expressed in macrophages and microglia and upregulated during cell activation. Also known as allograft-Inflammatory Factor 1 (AIF1), Iba1 has actin-bundling activity and participates in membrane ruffling and phagocytosis in activated microglia. As a biomarker for microglia Iba1 is used extensively in research into neuroinflammation and neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and different forms of dementia.
Wako’s Anti-Iba1 monoclonal NCNP27 is a mouse IgG2b primary antibody purified from the hybridoma supernatant of mouse clone NCNP27 by protein an affinity chromatography. The immunogen used is a synthetic peptide corresponding to the C terminus of human Iba1. Anti-Iba1 is specific to microglia and macrophages but will not cross react with neurons or astrocytes. This antibody is suitable for staining of a human paraffin section.
This antibody detects human Iba1 in tissue sections, recommended concentration for application on a human paraffin section of 1:100 – 1000
Clone: NCNP27
Cross reactivity: Human
Pack size - 50µl
Store at -20°C
For Research Use Only
Ionized calcium binding adaptor molecule 1 or Iba1 is specifically expressed in macrophages and microglia and upregulated during cell activation. Also known as allograft-Inflammatory Factor 1 (AIF1), Iba1 has actin-bundling activity and participates in membrane ruffling and phagocytosis in activated microglia. As a biomarker for microglia Iba1 is used extensively in research into neuroinflammation and neurodegenerative diseases, including Alzheimer’s, Parkinson’s, and different forms of dementia.
Wako’s Anti-Iba1 monoclonal NCNP27 is a mouse IgG2b primary antibody purified from the hybridoma supernatant of mouse clone NCNP27 by protein an affinity chromatography. The immunogen used is a synthetic peptide corresponding to the C terminus of human Iba1. Anti-Iba1 is specific to microglia and macrophages but will not cross react with neurons or astrocytes. This antibody is suitable for staining of a human paraffin section.
This antibody detects human Iba1 in tissue sections, recommended concentration for application on a human paraffin section of 1:100 – 1000
Clone: NCNP27
Cross reactivity: Human
Pack size - 50µl
Store at -20°C
For Research Use Only
Specification
- Brand FUJIFILM Wako Chemicals Europe GmbH – Lab Chem
- Sterile N
- CE Certified Research Use Only
- Warranty Period Standard Terms Apply
- Is product classified as dangerous goods? No
- Does the product contain latex? Unspecified
- Host Mouse
- Clonality Monoclonal
- Application Immunohistochemistry
- Form In TBS Solution
- Specificity C-Terminus of Human Iba1
- Species Reactivity Human (Other Species Have Not been Tested)
- Preparation Form NULL
- Concentration Indicated on Label
- Clone Number NCNP27
- Isotype IgG2b
- Source Species NULL
- Shelf Life NULL
- Cross Reactivity NULL
- Immunogen Synthetic Peptide Corresponding to the C-Terminus of Human Iba1
Storage Details
- Pack Description 50µL
- Shipping Condition Dry Ice
- Storage Condition -20
- Pack Length (m) 0.1
- Pack Width (m) 0.1
- Pack Height (m) 0.1
- Pack Weight (kg) 0.10
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